On this site, I am compiling interesting gene findings from studies on ME/CFS.
Basically, I add findings that a paper's authors propose as potentially interesting or which can be inferred by a reader as potentially interesting, and which can be described by the name of a single gene. Findings here are specifically positive findings (i.e. a gene won't be added based on a study not finding a difference from controls).
Genes added here could be based on genes nearest to or predicted to be affected by significant variants in a GWAS of ME/CFS, genes which are differentially expressed in ME/CFS, protein products of genes which are up- or down-regulated in ME/CFS, differential methylation associated with a gene, or other findings.
The goal is to be able to look up any given genes of interest and see how often and in which papers these genes have previously been mentioned as potentially promising.
Some decisions on whether to include a gene or not are slightly arbitrary because of the vast diversity of methodologies and types of findings in studies. Any interpretation of gene findings on this website should be based on reading the actual studies.
A note added on each study page is meant to provide the rationale for why certain genes were recorded. Keep in mind that sometimes the note only refers to one of multiple findings relating to a given gene, so one should read the full paper to see all relevant findings.
If you're interested in looking at the source code of the website, the repository is on Github at ruvilonix/sick-genes.
If you want to get in touch, send an email to contact@sickgenes.xyz.