APPL2

adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2

Details

HGNC: HGNC:18242
GeneCards: APPL2
NCBI: 55198
Ensembl: ENSG00000136044
UniProt: Q8NEU8
OMIM: 606231
UCSC: uc001tlf.2
VEGA: OTTHUMG00000169853
ENA: AY113704

Alias Symbols: FLJ10659, DIP13B
Previous Symbols: None
Alias Names: "DCC-interacting protein 13-beta"
Previous Names: "adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2"

Associated Studies

Transcriptional reprogramming primes CD8+ T cells toward exhaustion in Myalgic encephalomyelitis/chronic fatigue syndrome

2024 | Iu, David S.; Maya, Jessica; Vu, Luyen T.; Fogarty, Elizabeth A.; McNairn, Adrian J.; Ahmed, Faraz; Franconi, Carl J.; Munn, Paul R.; Grenier, Jennifer K.; Hanson, Maureen R.; Grimson, Andrew

Associated cohorts
Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - IOM (Institute of Medicine) 2015 criteria, Post-exertional malaise (PEM)

A pilot study on the immune cell proteome of long COVID patients shows changes to physiological pathways similar to those in myalgic encephalomyelitis/chronic fatigue syndrome

2023 | Peppercorn, Katie; Edgar, Christina D.; Kleffmann, Torsten; Tate, Warren P.

Associated cohorts
Phenotype: Long COVID, ME/CFS, ME/CFS - CCC criteria, ME/CFS - ICC Criteria, Post-exertional malaise (PEM)