C3

complement C3

Associated Studies

Charting the circulating proteome in ME/CFS using cross-system profiling to uncover mechanistic insights

2026 | Hoel et al.

Phenotype: ME/CFS, ME/CFS - Canadian Consensus Criteria (CCC) 2003, Post-exertional malaise (PEM)
Identification of Novel Reproducible Combinatorial Genetic Risk Factors for Myalgic Encephalomyelitis in the DecodeME Patient Cohort and Commonalities with Long COVID

2025 | Sardell et al.

Phenotype: ME/CFS
Data-independent LC-MS/MS analysis of ME/CFS plasma reveals a dysregulated coagulation system, endothelial dysfunction, downregulation of complement machinery

2024 | Nunes et al.

Phenotype: ME/CFS
Complement activation in a model of chronic fatigue syndrome

2003 | Sorensen et al.

Phenotype: ME/CFS, ME/CFS - Fukuda 1994 (CDC) Criteria

Details

HGNC: 1318
GeneCards: C3
NCBI: 718
Ensembl: ENSG00000125730
UniProt: P01024
OMIM: 120700
UCSC: uc002mfm.4
VEGA: OTTHUMG00000150335
ENA: J04763
Alias Symbols: CPAMD1, ARMD9, C3a, C3b
Previous Symbols: None
Alias Names: "C3a anaphylatoxin", "complement component C3a", "complement component C3b", "prepro-C3"
Previous Names: "complement component 3"