CASP8

caspase 8

Details

HGNC: HGNC:1509
GeneCards: CASP8
NCBI: 841
Ensembl: ENSG00000064012
UniProt: Q14790
OMIM: 601763
UCSC: uc002uxt.2
VEGA: OTTHUMG00000132821
ENA: U60520

Alias Symbols: MCH5, MACH, FLICE, Casp-8
Previous Symbols: None
Alias Names: None
Previous Names: "caspase 8, apoptosis-related cysteine protease", "caspase 8, apoptosis-related cysteine peptidase"

Associated Studies

HERV activation segregates ME/CFS from fibromyalgia while defining a novel nosologic entity

2025 | Giménez-Orenga, Karen; Martín-Martínez, Eva; Nathanson, Lubov; Oltra, Elisa

Associated cohorts
Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - ICC Criteria, Post-exertional malaise (PEM)
Phenotype: Fibromyalgia, Fibromyalgia - 1990 ACR (American College of Rheumatology) criteria, Fibromyalgia - 2011 ACR (American College of Rheumatology) criteria

Transcriptional reprogramming primes CD8+ T cells toward exhaustion in Myalgic encephalomyelitis/chronic fatigue syndrome

2024 | Iu, David S.; Maya, Jessica; Vu, Luyen T.; Fogarty, Elizabeth A.; McNairn, Adrian J.; Ahmed, Faraz; Franconi, Carl J.; Munn, Paul R.; Grenier, Jennifer K.; Hanson, Maureen R.; Grimson, Andrew

Associated cohorts
Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - IOM (Institute of Medicine) 2015 criteria, Post-exertional malaise (PEM)