CCL2

C-C motif chemokine ligand 2

Details

HGNC
HGNC:10618
GeneCards
CCL2
NCBI
6347
Ensembl
ENSG00000108691
UniProt
P13500
OMIM
158105
UCSC
uc002hhy.4
VEGA
OTTHUMG00000132887
ENA
BC009716
Alias Symbols
MCP1, MCP-1, MCAF, SMC-CF, GDCF-2, HC11, MGC9434
Previous Symbols
SCYA2
Alias Names
"monocyte chemotactic protein 1, homologous to mouse Sig-je", "monocyte chemoattractant protein-1", "monocyte chemotactic and activating factor", "monocyte secretory protein JE", "small inducible cytokine subfamily A (Cys-Cys), member 2"
Previous Names
"small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je)", "chemokine (C-C motif) ligand 2"

Associated Studies

Multifaceted evolution focused on maximal exploitation of domain knowledge for the consensus inference of Gene Regulatory Networks

2025 | Segura-Ortiz, Adrián; Giménez-Orenga, Karen; García-Nieto, José; Oltra, Elisa; Aldana-Montes, José F.

Associated cohorts
Phenotype: Fibromyalgia, Fibromyalgia - 1990 ACR (American College of Rheumatology) criteria, Fibromyalgia - 2011 ACR (American College of Rheumatology) criteria
Phenotype: Fibromyalgia, Fibromyalgia - 1990 ACR (American College of Rheumatology) criteria, Fibromyalgia - 2011 ACR (American College of Rheumatology) criteria, ME/CFS, ME/CFS - CCC criteria, ME/CFS - ICC Criteria, Post-exertional malaise (PEM)
Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - ICC Criteria, Post-exertional malaise (PEM)

Widespread Myalgia and Chronic Fatigue: Phagocytes from Macrophagic Myofasciitis Patients Exposed to Aluminum Oxyhydroxide-Adjuvanted Vaccine Exhibit Specific Inflammatory, Autophagic, and Mitochondrial Responses

2024 | Masson, Jean-Daniel; Badran, Ghidaa; Gherardi, Romain K.; Authier, François-Jérôme; Crépeaux, Guillemette

Associated cohorts
Phenotype: Chronic fatigue, Macrophagic myofasciitis, Myalgia

Transcriptional reprogramming primes CD8+ T cells toward exhaustion in Myalgic encephalomyelitis/chronic fatigue syndrome

2024 | Iu, David S.; Maya, Jessica; Vu, Luyen T.; Fogarty, Elizabeth A.; McNairn, Adrian J.; Ahmed, Faraz; Franconi, Carl J.; Munn, Paul R.; Grenier, Jennifer K.; Hanson, Maureen R.; Grimson, Andrew

Associated cohorts
Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - IOM (Institute of Medicine) 2015 criteria, Post-exertional malaise (PEM)

Immune exhaustion in ME/CFS and long COVID

2024 | Eaton-Fitch, Natalie; Rudd, Penny; Er, Teagan; Hool, Livia; Herrero, Lara; Marshall-Gradisnik, Sonya

Associated cohorts
Phenotype: Long COVID, Long COVID - CDC 2022 criteria

Diverse immunological dysregulation, chronic inflammation, and impaired erythropoiesis in long COVID patients with chronic fatigue syndrome

2024 | Saito, Suguru; Shahbaz, Shima; Osman, Mohammed; Redmond, Desiree; Bozorgmehr, Najmeh; Rosychuk, Rhonda J.; Lam, Grace; Sligl, Wendy; Cohen Tervaert, Jan Willem; Elahi, Shokrollah

Associated cohorts
Phenotype: Long COVID, ME/CFS, Post-exertional malaise (PEM)
Phenotype: Long COVID

Proteomics and cytokine analyses distinguish myalgic encephalomyelitis/chronic fatigue syndrome cases from controls

2023 | Giloteaux, Ludovic; Li, Jiayin; Hornig, Mady; Lipkin, W. Ian; Ruppert, David; Hanson, Maureen R.

Associated cohorts
Phenotype: ME/CFS, ME/CFS - Fukuda criteria