CCL3

C-C motif chemokine ligand 3

Details

HGNC
HGNC:10627
GeneCards
CCL3
NCBI
6348
Ensembl
ENSG00000277632
UniProt
P10147
OMIM
182283
UCSC
uc032gca.3
VEGA
OTTHUMG00000188413
ENA
M23178

Alias Symbols
G0S19-1, LD78ALPHA, MIP-1-alpha, LD78, SCI
Previous Symbols
SCYA3
Alias Names
"macrophage inflammatory protein 1 alpha"
Previous Names
"small inducible cytokine A3 (homologous to mouse Mip-1a)", "chemokine (C-C motif) ligand 3"

Associated Studies

Replicated blood-based biomarkers for myalgic encephalomyelitis not explicable by inactivity

2025 | Beentjes, Sjoerd Viktor; Miralles Méharon, Artur; Kaczmarczyk, Julia; Cassar, Amanda; Samms, Gemma Louise; Hejazi, Nima S; Khamseh, Ava; Ponting, Chris P

Associated cohorts
Phenotype: ME/CFS

HERV activation segregates ME/CFS from fibromyalgia while defining a novel nosologic entity

2025 | Giménez-Orenga, Karen; Martín-Martínez, Eva; Nathanson, Lubov; Oltra, Elisa

Associated cohorts
Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - ICC Criteria, Post-exertional malaise (PEM)
Phenotype: Fibromyalgia, Fibromyalgia - 1990 ACR (American College of Rheumatology) criteria, Fibromyalgia - 2011 ACR (American College of Rheumatology) criteria

Transcriptional reprogramming primes CD8+ T cells toward exhaustion in Myalgic encephalomyelitis/chronic fatigue syndrome

2024 | Iu, David S.; Maya, Jessica; Vu, Luyen T.; Fogarty, Elizabeth A.; McNairn, Adrian J.; Ahmed, Faraz; Franconi, Carl J.; Munn, Paul R.; Grenier, Jennifer K.; Hanson, Maureen R.; Grimson, Andrew

Associated cohorts
Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - IOM (Institute of Medicine) 2015 criteria, Post-exertional malaise (PEM)

Diverse immunological dysregulation, chronic inflammation, and impaired erythropoiesis in long COVID patients with chronic fatigue syndrome

2024 | Saito, Suguru; Shahbaz, Shima; Osman, Mohammed; Redmond, Desiree; Bozorgmehr, Najmeh; Rosychuk, Rhonda J.; Lam, Grace; Sligl, Wendy; Cohen Tervaert, Jan Willem; Elahi, Shokrollah

Associated cohorts
Phenotype: Long COVID, ME/CFS, Post-exertional malaise (PEM)

Association of circulating biomarkers with illness severity measures differentiates myalgic encephalomyelitis/chronic fatigue syndrome and post-COVID-19 condition: a prospective pilot cohort study

2024 | Domingo, Joan Carles; Battistini, Federica; Cordobilla, Begoña; Zaragozá, Maria Cleofé; Sanmartin-Sentañes, Ramón; Alegre-Martin, Jose; Cambras, Trinitat; Castro-Marrero, Jesus

Associated cohorts
Phenotype: Long COVID, Long COVID - 2021 WHO criteria