CXCL8

C-X-C motif chemokine ligand 8

Associated Studies

Integrated immune, hormonal, and transcriptomic profiling reveals sex-specific dysregulation in long COVID patients with ME/CFS

2025 | Shahbaz et al.

Phenotype: Long COVID, ME/CFS, ME/CFS - Canadian Consensus Criteria (CCC) 2003, Post-exertional malaise (PEM)
Heightened innate immunity may trigger chronic inflammation, fatigue and post-exertional malaise in ME/CFS

2025 | Che et al.

Phenotype: ME/CFS
Cerebrospinal fluid immune phenotyping reveals distinct immunotypes of myalgic encephalomyelitis/chronic fatigue syndrome

2025 | Bastos et al.

Phenotype: ME/CFS, ME/CFS - Canadian Consensus Criteria (CCC) 2003, Post-exertional malaise (PEM)
Cytokine signature associated with disease severity in chronic fatigue syndrome patients

2017 | Montoya et al.

Phenotype: ME/CFS, ME/CFS - Fukuda 1994 (CDC) Criteria

Details

HGNC: HGNC:6025
GeneCards: CXCL8
NCBI: 3576
Ensembl: ENSG00000169429
UniProt: P10145
OMIM: 146930
UCSC: None
VEGA: OTTHUMG00000151316
ENA: Y00787

Alias Symbols: SCYB8, LUCT, LECT, MDNCF, TSG-1, IL-8, NAP-1, 3-10C, MONAP, AMCF-I, LYNAP, NAF, b-ENAP, GCP-1, K60, GCP1, NAP1
Previous Symbols: IL8
Alias Names: "neutrophil-activating peptide 1", "granulocyte chemotactic protein 1", "monocyte-derived neutrophil chemotactic factor", "lung giant cell carcinoma-derived chemotactic protein", "tumor necrosis factor-induced gene 1", "monocyte-derived neutrophil-activating peptide", "lymphocyte derived neutrophil activating peptide", "beta endothelial cell-derived neutrophil activating peptide", "alveolar macrophage chemotactic factor I"
Previous Names: "interleukin 8", "chemokine (C-X-C motif) ligand 8"