FURIN

furin, paired basic amino acid cleaving enzyme

Details

HGNC: HGNC:8568
GeneCards: FURIN
NCBI: 5045
Ensembl: ENSG00000140564
UniProt: P09958
OMIM: 136950
UCSC: uc002bpu.2
VEGA: OTTHUMG00000149831
ENA: X17094
Alias Symbols: SPC1
Previous Symbols: PCSK3, FUR, PACE
Alias Names: "proprotein convertase subtilisin/kexin 3", "subtilisin-like proprotein convertase 1"
Previous Names: "paired basic amino acid cleaving enzyme (furin, membrane associated receptor protein)", "furin (paired basic amino acid cleaving enzyme)"

Associated Studies

Replicated blood-based biomarkers for myalgic encephalomyelitis not explicable by inactivity

2025 | Beentjes, Sjoerd Viktor; Miralles Méharon, Artur; Kaczmarczyk, Julia; Cassar, Amanda; Samms, Gemma Louise; Hejazi, Nima S; Khamseh, Ava; Ponting, Chris P

Associated cohorts
Phenotype: ME/CFS

Transcriptional reprogramming primes CD8+ T cells toward exhaustion in Myalgic encephalomyelitis/chronic fatigue syndrome

2024 | Iu, David S.; Maya, Jessica; Vu, Luyen T.; Fogarty, Elizabeth A.; McNairn, Adrian J.; Ahmed, Faraz; Franconi, Carl J.; Munn, Paul R.; Grenier, Jennifer K.; Hanson, Maureen R.; Grimson, Andrew

Associated cohorts
Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - IOM (Institute of Medicine) 2015 criteria, Post-exertional malaise (PEM)