GZMB

granzyme B

Details

HGNC: HGNC:4709
GeneCards: GZMB
NCBI: 3002
Ensembl: ENSG00000100453
UniProt: P10144
OMIM: 123910
UCSC: uc001wps.4
VEGA: OTTHUMG00000029369
ENA: BC030195
Alias Symbols: CCPI, CGL-1, CSP-B, CGL1, CTSGL1, HLP, SECT
Previous Symbols: CTLA1, CSPB
Alias Names: "fragmentin 2", "cytotoxic serine protease B", "cathepsin G-like 1", "T-cell serine protease 1-3E", "granzyme 2", "cytotoxic T-lymphocyte-associated serine esterase 1"
Previous Names: "granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)"

Associated Studies

Transcriptional reprogramming primes CD8+ T cells toward exhaustion in Myalgic encephalomyelitis/chronic fatigue syndrome

2024 | Iu, David S.; Maya, Jessica; Vu, Luyen T.; Fogarty, Elizabeth A.; McNairn, Adrian J.; Ahmed, Faraz; Franconi, Carl J.; Munn, Paul R.; Grenier, Jennifer K.; Hanson, Maureen R.; Grimson, Andrew

Associated cohorts
Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - IOM (Institute of Medicine) 2015 criteria, Post-exertional malaise (PEM)

Immunometabolic changes and potential biomarkers in CFS peripheral immune cells revealed by single-cell RNA sequencing

2024 | Sun, Yujing; Zhang, Zhenhua; Qiao, Qincheng; Zou, Ying; Wang, Lina; Wang, Tixiao; Lou, Bo; Li, Guosheng; Xu, Miao; Wang, Yanxiang; Zhang, Zhenhong; Hou, Xinguo; Chen, Li; Zhao, Ruxing

Associated cohorts
Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - Fukuda criteria, ME/CFS - IOM (Institute of Medicine) 2015 criteria, Post-exertional malaise (PEM)