HLA-DRB1

major histocompatibility complex, class II, DR beta 1

Details

HGNC
HGNC:4948
GeneCards
HLA-DRB1
NCBI
3123
Ensembl
ENSG00000196126
UniProt
P01911
OMIM
142857
UCSC
uc003obp.5
VEGA
OTTHUMG00000031196
ENA
AJ297583

Alias Symbols
None
Previous Symbols
HLA-DR1B
Alias Names
None
Previous Names
None

Associated Studies

Multifaceted evolution focused on maximal exploitation of domain knowledge for the consensus inference of Gene Regulatory Networks

2025 | Segura-Ortiz, Adrián; Giménez-Orenga, Karen; García-Nieto, José; Oltra, Elisa; Aldana-Montes, José F.

Associated cohorts
Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - ICC Criteria, Post-exertional malaise (PEM)
Phenotype: Fibromyalgia, Fibromyalgia - 1990 ACR (American College of Rheumatology) criteria, Fibromyalgia - 2011 ACR (American College of Rheumatology) criteria

HERV activation segregates ME/CFS from fibromyalgia while defining a novel nosologic entity

2025 | Giménez-Orenga, Karen; Martín-Martínez, Eva; Nathanson, Lubov; Oltra, Elisa

Associated cohorts
Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - ICC Criteria, Post-exertional malaise (PEM)
Phenotype: Fibromyalgia, Fibromyalgia - 1990 ACR (American College of Rheumatology) criteria, Fibromyalgia - 2011 ACR (American College of Rheumatology) criteria

Transcriptional reprogramming primes CD8+ T cells toward exhaustion in Myalgic encephalomyelitis/chronic fatigue syndrome

2024 | Iu, David S.; Maya, Jessica; Vu, Luyen T.; Fogarty, Elizabeth A.; McNairn, Adrian J.; Ahmed, Faraz; Franconi, Carl J.; Munn, Paul R.; Grenier, Jennifer K.; Hanson, Maureen R.; Grimson, Andrew

Associated cohorts
Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - IOM (Institute of Medicine) 2015 criteria, Post-exertional malaise (PEM)

Immunometabolic changes and potential biomarkers in CFS peripheral immune cells revealed by single-cell RNA sequencing

2024 | Sun, Yujing; Zhang, Zhenhua; Qiao, Qincheng; Zou, Ying; Wang, Lina; Wang, Tixiao; Lou, Bo; Li, Guosheng; Xu, Miao; Wang, Yanxiang; Zhang, Zhenhong; Hou, Xinguo; Chen, Li; Zhao, Ruxing

Associated cohorts
Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - Fukuda criteria, ME/CFS - IOM (Institute of Medicine) 2015 criteria, Post-exertional malaise (PEM)

Immune exhaustion in ME/CFS and long COVID

2024 | Eaton-Fitch, Natalie; Rudd, Penny; Er, Teagan; Hool, Livia; Herrero, Lara; Marshall-Gradisnik, Sonya

Associated cohorts
Phenotype: Long COVID, Long COVID - CDC 2022 criteria