HSPA5

heat shock protein family A (Hsp70) member 5

Details

HGNC: HGNC:5238
GeneCards: HSPA5
NCBI: 3309
Ensembl: ENSG00000044574
UniProt: P11021
OMIM: 138120
UCSC: uc004bpn.4
VEGA: OTTHUMG00000020672
ENA: None
Alias Symbols: BiP
Previous Symbols: GRP78
Alias Names: "glucose-regulated protein, 78kDa"
Previous Names: "heat shock 70kD protein 5 (glucose-regulated protein, 78kD)", "heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)"

Associated Studies

Extracellular vesicle proteomics uncovers energy metabolism, complement system, and endoplasmic reticulum stress response dysregulation postexercise in males with myalgic encephalomyelitis/chronic fatigue syndrome

2025 | Glass, Katherine A.; Giloteaux, Ludovic; Zhang, Sheng; Hanson, Maureen R.

Associated cohorts
Phenotype: ME/CFS, ME/CFS - CCC criteria, Post-exertional malaise (PEM)

Transcriptional reprogramming primes CD8+ T cells toward exhaustion in Myalgic encephalomyelitis/chronic fatigue syndrome

2024 | Iu, David S.; Maya, Jessica; Vu, Luyen T.; Fogarty, Elizabeth A.; McNairn, Adrian J.; Ahmed, Faraz; Franconi, Carl J.; Munn, Paul R.; Grenier, Jennifer K.; Hanson, Maureen R.; Grimson, Andrew

Associated cohorts
Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - IOM (Institute of Medicine) 2015 criteria, Post-exertional malaise (PEM)

Dysregulation of extracellular vesicle protein cargo in female myalgic encephalomyelitis/chronic fatigue syndrome cases and sedentary controls in response to maximal exercise

2024 | Giloteaux, Ludovic; Glass, Katherine A.; Germain, Arnaud; Franconi, Carl J.; Zhang, Sheng; Hanson, Maureen R.

Associated cohorts
Phenotype: ME/CFS, ME/CFS - CCC criteria, Post-exertional malaise (PEM)

WASF3 disrupts mitochondrial respiration and may mediate exercise intolerance in myalgic encephalomyelitis/chronic fatigue syndrome

2023 | Wang, Ping-yuan; Ma, Jin; Kim, Young-Chae; Son, Annie Y.; Syed, Abu Mohammad; Liu, Chengyu; Mori, Mateus P.; Huffstutler, Rebecca D.; Stolinski, JoEllyn L.; Talagala, S. Lalith; Kang, Ju-Gyeong; Walitt, Brian T.; Nath, Avindra; Hwang, Paul M.

Associated cohorts
Phenotype: ME/CFS