IL6

interleukin 6

Associated Studies

Microvascular Remodeling and Endothelial Dysfunction Across Post-COVID-19 and ME/CFS: Insights from the All Eyes on PCS Study

2026 | Wallraven et al.

Phenotype: Long COVID, ME/CFS, ME/CFS - Canadian Consensus Criteria (CCC) 2003, Post-exertional malaise (PEM)
SMPDL3B a novel biomarker and therapeutic target in myalgic encephalomyelitis

2025 | Rostami-Afshari et al.

Phenotype: ME/CFS, ME/CFS - Canadian Consensus Criteria (CCC) 2003, Post-exertional malaise (PEM)
Integrated immune, hormonal, and transcriptomic profiling reveals sex-specific dysregulation in long COVID patients with ME/CFS

2025 | Shahbaz et al.

Phenotype: Long COVID, ME/CFS, ME/CFS - Canadian Consensus Criteria (CCC) 2003, Post-exertional malaise (PEM)
Heightened innate immunity may trigger chronic inflammation, fatigue and post-exertional malaise in ME/CFS

2025 | Che et al.

Phenotype: ME/CFS
Blood parameters differentiate post COVID-19 condition from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Fibromyalgia

2025 | Giménez-Orenga et al.

Phenotype: ME/CFS
Identifying the molecular dynamics of stress in chronic fatigue syndrome

2024 | Paplomatas et al.

Phenotype: ME/CFS, ME/CFS - Canadian Consensus Criteria (CCC) 2003, ME/CFS - Fukuda 1994 (CDC) Criteria, Post-exertional malaise (PEM)
Circulating miRNAs Expression in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

2023 | Soffritti et al.

Phenotype: ME/CFS, ME/CFS - Fukuda 1994 (CDC) Criteria
MCP-1 is increased in patients with CFS and FM, whilst several other immune markers are significantly lower than healthy controls

2020 | Groven et al.

Phenotype: ME/CFS, ME/CFS - Fukuda 1994 (CDC) Criteria
Gene Expression Factor Analysis to Differentiate Pathways Linked to Fibromyalgia, Chronic Fatigue Syndrome, and Depression in a Diverse Patient Sample

2015 | Iacob et al.

Phenotype: ME/CFS, ME/CFS - Fukuda 1994 (CDC) Criteria
Abnormalities of AMPK Activation and Glucose Uptake in Cultured Skeletal Muscle Cells from Individuals with Chronic Fatigue Syndrome

2015 | Brown et al.

Phenotype: ME/CFS, ME/CFS - Fukuda 1994 (CDC) Criteria

Details

HGNC: 6018
GeneCards: IL6
NCBI: 3569
Ensembl: ENSG00000136244
UniProt: P05231
OMIM: 147620
UCSC: uc064bxs.1
VEGA: OTTHUMG00000023178
ENA: M18403
Alias Symbols: IL-6, BSF2, HGF, HSF
Previous Symbols: IFNB2
Alias Names: "interferon, beta 2"
Previous Names: "interleukin 6 (interferon, beta 2)"