IL6ST

interleukin 6 cytokine family signal transducer

Details

HGNC: HGNC:6021
GeneCards: IL6ST
NCBI: 3572
Ensembl: ENSG00000134352
UniProt: P40189
OMIM: 600694
UCSC: uc003jqq.4
VEGA: OTTHUMG00000097043
ENA: M57230
Alias Symbols: GP130, CD130, sGP130, IL-6RB
Previous Symbols: None
Alias Names: "gp130, oncostatin M receptor", "Interleukin-6 receptor subunit beta", "membrane glycoprotein 130"
Previous Names: "interleukin 6 signal transducer (gp130, oncostatin M receptor)", "interleukin 6 signal transducer"

Associated Studies

Upregulation of olfactory receptors and neuronal-associated genes highlights complex immune and neuronal dysregulation in Long COVID patients

2025 | Shahbaz, Shima; Rezaeifar, Maryam; Syed, Hussein; Redmond, Desiree; Terveart, Jan Willem Cohen; Osman, Mohammed; Elahi, Shokrollah

Associated cohorts

Phenotype: Long COVID, ME/CFS, ME/CFS - CCC criteria, Post-exertional malaise (PEM)

HERV activation segregates ME/CFS from fibromyalgia while defining a novel nosologic entity

2025 | Giménez-Orenga, Karen; Martín-Martínez, Eva; Nathanson, Lubov; Oltra, Elisa

Associated cohorts

Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - ICC Criteria, Post-exertional malaise (PEM)

Phenotype: Fibromyalgia, Fibromyalgia - 1990 ACR (American College of Rheumatology) criteria, Fibromyalgia - 2011 ACR (American College of Rheumatology) criteria

Phenotype: Fibromyalgia, Fibromyalgia - 1990 ACR (American College of Rheumatology) criteria, Fibromyalgia - 2011 ACR (American College of Rheumatology) criteria, ME/CFS, ME/CFS - CCC criteria, ME/CFS - ICC Criteria, Post-exertional malaise (PEM)

Transcriptional reprogramming primes CD8+ T cells toward exhaustion in Myalgic encephalomyelitis/chronic fatigue syndrome

2024 | Iu, David S.; Maya, Jessica; Vu, Luyen T.; Fogarty, Elizabeth A.; McNairn, Adrian J.; Ahmed, Faraz; Franconi, Carl J.; Munn, Paul R.; Grenier, Jennifer K.; Hanson, Maureen R.; Grimson, Andrew

Associated cohorts

Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - IOM (Institute of Medicine) 2015 criteria, Post-exertional malaise (PEM)