ITGAM

integrin subunit alpha M

Details

HGNC: HGNC:6149
GeneCards: ITGAM
NCBI: 3684
Ensembl: ENSG00000169896
UniProt: P11215
OMIM: 120980
UCSC: uc002ebq.4
VEGA: OTTHUMG00000176612
ENA: J03925
Alias Symbols: MAC-1, CD11b
Previous Symbols: CR3A, CD11B
Alias Names: "complement component 3 receptor 3 subunit", "macrophage-1 antigen alpha subunit"
Previous Names: "integrin, alpha M (complement component receptor 3, alpha; also known as CD11b (p170), macrophage antigen alpha polypeptide)", "integrin, alpha M (complement component 3 receptor 3 subunit)"

Associated Studies

Replicated blood-based biomarkers for myalgic encephalomyelitis not explicable by inactivity

2025 | Beentjes, Sjoerd Viktor; Miralles Méharon, Artur; Kaczmarczyk, Julia; Cassar, Amanda; Samms, Gemma Louise; Hejazi, Nima S; Khamseh, Ava; Ponting, Chris P

Associated cohorts
Phenotype: ME/CFS

HERV activation segregates ME/CFS from fibromyalgia while defining a novel nosologic entity

2025 | Giménez-Orenga, Karen; Martín-Martínez, Eva; Nathanson, Lubov; Oltra, Elisa

Associated cohorts
Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - ICC Criteria, Post-exertional malaise (PEM)
Phenotype: Fibromyalgia, Fibromyalgia - 1990 ACR (American College of Rheumatology) criteria, Fibromyalgia - 2011 ACR (American College of Rheumatology) criteria

Single-cell transcriptomics of the immune system in ME/CFS at baseline and following symptom provocation

2024 | Vu, Luyen Tien; Ahmed, Faraz; Zhu, Hongya; Iu, David Shing Huk; Fogarty, Elizabeth A.; Kwak, Yeonui; Chen, Weizhong; Franconi, Carl J.; Munn, Paul R.; Tate, Ann E.; Levine, Susan M.; Stevens, Jared; Mao, Xiangling; Shungu, Dikoma C.; Moore, Geoffrey E.; Keller, Betsy A.; Hanson, Maureen R.; Grenier, Jennifer K.; Grimson, Andrew

Associated cohorts
Phenotype: ME/CFS, ME/CFS - CCC criteria, Post-exertional malaise (PEM)