ITGB2

integrin subunit beta 2

Details

HGNC: HGNC:6155
GeneCards: ITGB2
NCBI: 3689
Ensembl: ENSG00000160255
UniProt: P05107
OMIM: 600065
UCSC: uc002zgf.5
VEGA: OTTHUMG00000090257
ENA: AK222505
Alias Symbols: LFA-1, MAC-1
Previous Symbols: CD18, MFI7
Alias Names: "complement component 3 receptor 3 and 4 subunit"
Previous Names: "integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit)", "integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)"

Associated Studies

Upregulation of olfactory receptors and neuronal-associated genes highlights complex immune and neuronal dysregulation in Long COVID patients

2025 | Shahbaz, Shima; Rezaeifar, Maryam; Syed, Hussein; Redmond, Desiree; Terveart, Jan Willem Cohen; Osman, Mohammed; Elahi, Shokrollah

Associated cohorts

Phenotype: Long COVID, ME/CFS, ME/CFS - CCC criteria, Post-exertional malaise (PEM)

Transcriptional reprogramming primes CD8+ T cells toward exhaustion in Myalgic encephalomyelitis/chronic fatigue syndrome

2024 | Iu, David S.; Maya, Jessica; Vu, Luyen T.; Fogarty, Elizabeth A.; McNairn, Adrian J.; Ahmed, Faraz; Franconi, Carl J.; Munn, Paul R.; Grenier, Jennifer K.; Hanson, Maureen R.; Grimson, Andrew

Associated cohorts

Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - IOM (Institute of Medicine) 2015 criteria, Post-exertional malaise (PEM)

Immunometabolic changes and potential biomarkers in CFS peripheral immune cells revealed by single-cell RNA sequencing

2024 | Sun, Yujing; Zhang, Zhenhua; Qiao, Qincheng; Zou, Ying; Wang, Lina; Wang, Tixiao; Lou, Bo; Li, Guosheng; Xu, Miao; Wang, Yanxiang; Zhang, Zhenhong; Hou, Xinguo; Chen, Li; Zhao, Ruxing

Associated cohorts

Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - Fukuda criteria, ME/CFS - IOM (Institute of Medicine) 2015 criteria, Post-exertional malaise (PEM)