ITIH4

inter-alpha-trypsin inhibitor heavy chain 4

Details

HGNC: HGNC:6169
GeneCards: ITIH4
NCBI: 3700
Ensembl: ENSG00000055955
UniProt: Q14624
OMIM: 600564
UCSC: uc003dfz.4
VEGA: OTTHUMG00000159023
ENA: D38535
Alias Symbols: IHRP, H4P
Previous Symbols: ITIHL1
Alias Names: "plasma Kallikrein-sensitive glycoprotein"
Previous Names: "inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein)", "inter-alpha-trypsin inhibitor heavy chain family, member 4"

Associated Studies

Replicated blood-based biomarkers for myalgic encephalomyelitis not explicable by inactivity

2025 | Beentjes, Sjoerd Viktor; Miralles Méharon, Artur; Kaczmarczyk, Julia; Cassar, Amanda; Samms, Gemma Louise; Hejazi, Nima S; Khamseh, Ava; Ponting, Chris P

Associated cohorts
Phenotype: ME/CFS

Dysregulation of extracellular vesicle protein cargo in female myalgic encephalomyelitis/chronic fatigue syndrome cases and sedentary controls in response to maximal exercise

2024 | Giloteaux, Ludovic; Glass, Katherine A.; Germain, Arnaud; Franconi, Carl J.; Zhang, Sheng; Hanson, Maureen R.

Associated cohorts
Phenotype: ME/CFS, ME/CFS - CCC criteria, Post-exertional malaise (PEM)

Data-independent LC-MS/MS analysis of ME/CFS plasma reveals a dysregulated coagulation system, endothelial dysfunction, downregulation of complement machinery

2024 | Nunes, Massimo; Vlok, Mare; Proal, Amy; Kell, Douglas B.; Pretorius, Etheresia

Associated cohorts
Phenotype: ME/CFS