LEP

leptin

Details

HGNC: HGNC:6553
GeneCards: LEP
NCBI: 3952
Ensembl: ENSG00000174697
UniProt: P41159
OMIM: 164160
UCSC: uc003vml.3
VEGA: OTTHUMG00000157564
ENA: None
Alias Symbols: None
Previous Symbols: OBS, OB
Alias Names: None
Previous Names: "leptin (murine obesity homolog)", "leptin (obesity homolog, mouse)"

Associated Studies

Replicated blood-based biomarkers for myalgic encephalomyelitis not explicable by inactivity

2025 | Beentjes, Sjoerd Viktor; Miralles Méharon, Artur; Kaczmarczyk, Julia; Cassar, Amanda; Samms, Gemma Louise; Hejazi, Nima S; Khamseh, Ava; Ponting, Chris P

Associated cohorts
Phenotype: ME/CFS

Longitudinal cytokine and multi-modal health data of an extremely severe ME/CFS patient with HSD reveals insights into immunopathology, and disease severity

2024 | Jahanbani, Fereshteh; Sing, Justin Cyril; Maynard, Rajan Douglas; Jahanbani, Shaghayegh; Dafoe, Janet; Dafoe, Whitney; Jones, Nathan; Wallace, Kelvin J.; Rastan, Azuravesta; Maecker, Holden T.; Röst, Hannes L.; Snyder, Michael P.; Davis, Ronald W.

Associated cohorts
Phenotype: Hypermobility spectrum disorder, ME/CFS, ME/CFS - CCC criteria, ME/CFS - ICC Criteria, Post-exertional malaise (PEM), Postural Orthostatic Tachycardia Syndrome (POTS)

Association of circulating biomarkers with illness severity measures differentiates myalgic encephalomyelitis/chronic fatigue syndrome and post-COVID-19 condition: a prospective pilot cohort study

2024 | Domingo, Joan Carles; Battistini, Federica; Cordobilla, Begoña; Zaragozá, Maria Cleofé; Sanmartin-Sentañes, Ramón; Alegre-Martin, Jose; Cambras, Trinitat; Castro-Marrero, Jesus

Associated cohorts
Phenotype: ME/CFS, ME/CFS - ICC Criteria, Post-exertional malaise (PEM)

Proteomics and cytokine analyses distinguish myalgic encephalomyelitis/chronic fatigue syndrome cases from controls

2023 | Giloteaux, Ludovic; Li, Jiayin; Hornig, Mady; Lipkin, W. Ian; Ruppert, David; Hanson, Maureen R.

Associated cohorts
Phenotype: ME/CFS, ME/CFS - Fukuda criteria