MAP2K4

mitogen-activated protein kinase kinase 4

Details

HGNC: HGNC:6844
GeneCards: MAP2K4
NCBI: 6416
Ensembl: ENSG00000065559
UniProt: P45985
OMIM: 601335
UCSC: uc002gnj.5
VEGA: OTTHUMG00000178267
ENA: L36870
Alias Symbols: MEK4, JNKK1, PRKMK4, MKK4, MAPKK4, SAPKK1, SKK1, JNKK, SEK1
Previous Symbols: SERK1
Alias Names: "stress-activated protein kinase kinase 1", "c-Jun NH2-terminal kinase kinase 1"
Previous Names: "SAPK/ERK kinase 1"

Associated Studies

Upregulation of olfactory receptors and neuronal-associated genes highlights complex immune and neuronal dysregulation in Long COVID patients

2025 | Shahbaz, Shima; Rezaeifar, Maryam; Syed, Hussein; Redmond, Desiree; Terveart, Jan Willem Cohen; Osman, Mohammed; Elahi, Shokrollah

Associated cohorts

Phenotype: Long COVID, ME/CFS, ME/CFS - CCC criteria, Post-exertional malaise (PEM)