MT-CO1

mitochondrially encoded cytochrome c oxidase I

Associated Studies

Systematic Examination of Gene Expression and Proteomic Evidence Across Tissues Supports the Role of Mitochondrial Dysregulation in ME/CFS

2026 | Keele et al.

Phenotype: ME/CFS
Metabolic adaptation and fragility in healthy 3D in vitro skeletal muscle tissues exposed to chronic fatigue syndrome and Long COVID-19 sera

2025 | Mughal et al.

Phenotype: ME/CFS, ME/CFS - International Consensus Criteria (ICC), Post-exertional malaise (PEM)
Mitochondrial DNA Missense Mutations ChrMT: 8981A > G and ChrMT: 6268C > T Identified in a Caucasian Female with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Triggered by the Epstein–Barr Virus

2024 | Tang-Siegel et al.

Phenotype: ME/CFS, ME/CFS - Fukuda 1994 (CDC) Criteria, Post-exertional malaise (PEM)
WASF3 disrupts mitochondrial respiration and may mediate exercise intolerance in myalgic encephalomyelitis/chronic fatigue syndrome

2023 | Wang et al.

Phenotype: ME/CFS, Post-exertional malaise (PEM)

Details

HGNC: 7419
GeneCards: MT-CO1
NCBI: 4512
Ensembl: ENSG00000198804
UniProt: P00395
OMIM: 516030
UCSC: uc031tga.3
VEGA: None
ENA: None
Alias Symbols: COX1, COI
Previous Symbols: MTCO1
Alias Names: None
Previous Names: "cytochrome c oxidase I"