P4HB

prolyl 4-hydroxylase subunit beta

Details

HGNC
HGNC:8548
GeneCards
P4HB
NCBI
5034
Ensembl
ENSG00000185624
UniProt
P07237
OMIM
176790
UCSC
uc002kbn.2
VEGA
OTTHUMG00000150269
ENA
J02783
Alias Symbols
PDIA1, PROHB, DSI, GIT, PDI, PO4HB, P4Hbeta
Previous Symbols
PO4DB, ERBA2L
Alias Names
"protein disulfide isomerase-associated 1", "protein disulfide isomerase family A, member 1", "collagen prolyl 4-hydroxylase beta"
Previous Names
"procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide (protein disulfide isomerase; thyroid hormone binding protein p55)", "procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide (protein disulfide isomerase-associated 1)", "procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide", "prolyl 4-hydroxylase, beta polypeptide"

Associated Studies

Upregulation of olfactory receptors and neuronal-associated genes highlights complex immune and neuronal dysregulation in Long COVID patients

2025 | Shahbaz, Shima; Rezaeifar, Maryam; Syed, Hussein; Redmond, Desiree; Terveart, Jan Willem Cohen; Osman, Mohammed; Elahi, Shokrollah

Associated cohorts
Phenotype: Long COVID, ME/CFS, ME/CFS - CCC criteria, Post-exertional malaise (PEM)

Extracellular vesicle proteomics uncovers energy metabolism, complement system, and endoplasmic reticulum stress response dysregulation postexercise in males with myalgic encephalomyelitis/chronic fatigue syndrome

2025 | Glass, Katherine A.; Giloteaux, Ludovic; Zhang, Sheng; Hanson, Maureen R.

Associated cohorts
Phenotype: ME/CFS, ME/CFS - CCC criteria, Post-exertional malaise (PEM)

Transcriptional reprogramming primes CD8+ T cells toward exhaustion in Myalgic encephalomyelitis/chronic fatigue syndrome

2024 | Iu, David S.; Maya, Jessica; Vu, Luyen T.; Fogarty, Elizabeth A.; McNairn, Adrian J.; Ahmed, Faraz; Franconi, Carl J.; Munn, Paul R.; Grenier, Jennifer K.; Hanson, Maureen R.; Grimson, Andrew

Associated cohorts
Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - IOM (Institute of Medicine) 2015 criteria, Post-exertional malaise (PEM)

Dysregulation of extracellular vesicle protein cargo in female myalgic encephalomyelitis/chronic fatigue syndrome cases and sedentary controls in response to maximal exercise

2024 | Giloteaux, Ludovic; Glass, Katherine A.; Germain, Arnaud; Franconi, Carl J.; Zhang, Sheng; Hanson, Maureen R.

Associated cohorts
Phenotype: ME/CFS, ME/CFS - CCC criteria, Post-exertional malaise (PEM)

Deep phenotyping of post-infectious myalgic encephalomyelitis/chronic fatigue syndrome

2024 | Walitt, Brian; Singh, Komudi; LaMunion, Samuel R.; Hallett, Mark; Jacobson, Steve; Chen, Kong; Enose-Akahata, Yoshimi; Apps, Richard; Barb, Jennifer J.; Bedard, Patrick; Brychta, Robert J.; Buckley, Ashura Williams; Burbelo, Peter D.; Calco, Brice; Cathay, Brianna; Chen, Li; Chigurupati, Snigdha; Chen, Jinguo; Cheung, Foo; Chin, Lisa M. K.; Coleman, Benjamin W.; Courville, Amber B.; Deming, Madeleine S.; Drinkard, Bart; Feng, Li Rebekah; Ferrucci, Luigi; Gabel, Scott A.; Gavin, Angelique; Goldstein, David S.; Hassanzadeh, Shahin; Horan, Sean C.; Horovitz, Silvina G.; Johnson, Kory R.; Govan, Anita Jones; Knutson, Kristine M.; Kreskow, Joy D.; Levin, Mark; Lyons, Jonathan J.; Madian, Nicholas; Malik, Nasir; Mammen, Andrew L.; McCulloch, John A.; McGurrin, Patrick M.; Milner, Joshua D.; Moaddel, Ruin; Mueller, Geoffrey A.; Mukherjee, Amrita; Muñoz-Braceras, Sandra; Norato, Gina; Pak, Katherine; Pinal-Fernandez, Iago; Popa, Traian; Reoma, Lauren B.; Sack, Michael N.; Safavi, Farinaz; Saligan, Leorey N.; Sellers, Brian A.; Sinclair, Stephen; Smith, Bryan; Snow, Joseph; Solin, Stacey; Stussman, Barbara J.; Trinchieri, Giorgio; Turner, Sara A.; Vetter, C. Stephenie; Vial, Felipe; Vizioli, Carlotta; Williams, Ashley; Yang, Shanna B.; Nath, Avindra

Associated cohorts
Phenotype: ME/CFS, ME/CFS - IOM (Institute of Medicine) 2015 criteria, Post-exertional malaise (PEM)