PDHA1

pyruvate dehydrogenase E1 subunit alpha 1

Associated Studies

Metabolic adaptation and fragility in healthy 3D in vitro skeletal muscle tissues exposed to chronic fatigue syndrome and Long COVID-19 sera

2025 | Mughal et al.

Phenotype: ME/CFS, ME/CFS - International Consensus Criteria (ICC), Post-exertional malaise (PEM)
Metabolic profiling indicates impaired pyruvate dehydrogenase function in myalgic encephalopathy/chronic fatigue syndrome

2016 | Fluge et al.

Phenotype: ME/CFS, ME/CFS - Canadian Consensus Criteria (CCC) 2003, Post-exertional malaise (PEM)

Details

HGNC: HGNC:8806
GeneCards: PDHA1
NCBI: 5160
Ensembl: ENSG00000131828
UniProt: P08559
OMIM: 300502
UCSC: uc011mjc.3
VEGA: OTTHUMG00000021224
ENA: None
Alias Symbols: E1alpha
Previous Symbols: PDHA
Alias Names: "pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial"
Previous Names: "pyruvate dehydrogenase (lipoamide) alpha 1", "pyruvate dehydrogenase alpha 1"