SERPINA3

serpin family A member 3

Details

HGNC
HGNC:16
GeneCards
SERPINA3
NCBI
12
Ensembl
ENSG00000196136
UniProt
P01011
OMIM
107280
UCSC
uc001yds.4
VEGA
OTTHUMG00000029851
ENA
K01500
Alias Symbols
ACT
Previous Symbols
AACT
Alias Names
"alpha-1 antichymotrypsin"
Previous Names
"alpha-1-antichymotrypsin", "serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3", "serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3"

Associated Studies

Replicated blood-based biomarkers for myalgic encephalomyelitis not explicable by inactivity

2025 | Beentjes, Sjoerd Viktor; Miralles Méharon, Artur; Kaczmarczyk, Julia; Cassar, Amanda; Samms, Gemma Louise; Hejazi, Nima S; Khamseh, Ava; Ponting, Chris P

Associated cohorts
Phenotype: ME/CFS

Dysregulation of extracellular vesicle protein cargo in female myalgic encephalomyelitis/chronic fatigue syndrome cases and sedentary controls in response to maximal exercise

2024 | Giloteaux, Ludovic; Glass, Katherine A.; Germain, Arnaud; Franconi, Carl J.; Zhang, Sheng; Hanson, Maureen R.

Associated cohorts
Phenotype: ME/CFS, ME/CFS - CCC criteria, Post-exertional malaise (PEM)

Plasma proteomic profiling suggests an association between antigen driven clonal B cell expansion and ME/CFS

2020 | Milivojevic, Milica; Che, Xiaoyu; Bateman, Lucinda; Cheng, Aaron; Garcia, Benjamin A.; Hornig, Mady; Huber, Manuel; Klimas, Nancy G.; Lee, Bohyun; Lee, Hyoungjoo; Levine, Susan; Montoya, Jose G.; Peterson, Daniel L.; Komaroff, Anthony L.; Lipkin, W. Ian

Associated cohorts
Phenotype: ME/CFS
Phenotype: Irritable bowel syndrome, ME/CFS

A chronic fatigue syndrome – related proteome in human cerebrospinal fluid

2005 | Baraniuk, James N; Casado, Begona; Maibach, Hilda; Clauw, Daniel J; Pannell, Lewis K; Hess S, Sonja

Associated cohorts
Phenotype: Fibromyalgia, Gulf War syndrome, ME/CFS