STAT3

signal transducer and activator of transcription 3

Details

HGNC: HGNC:11364
GeneCards: STAT3
NCBI: 6774
Ensembl: ENSG00000168610
UniProt: P40763
OMIM: 102582
UCSC: uc002hzl.2
VEGA: OTTHUMG00000150645
ENA: BC014482
Alias Symbols: APRF
Previous Symbols: None
Alias Names: None
Previous Names: "signal transducer and activator of transcription 3 (acute-phase response factor)"

Associated Studies

HERV activation segregates ME/CFS from fibromyalgia while defining a novel nosologic entity

2025 | Giménez-Orenga, Karen; Martín-Martínez, Eva; Nathanson, Lubov; Oltra, Elisa

Associated cohorts

Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - ICC Criteria, Post-exertional malaise (PEM)

Phenotype: Fibromyalgia, Fibromyalgia - 1990 ACR (American College of Rheumatology) criteria, Fibromyalgia - 2011 ACR (American College of Rheumatology) criteria

Transcriptional reprogramming primes CD8+ T cells toward exhaustion in Myalgic encephalomyelitis/chronic fatigue syndrome

2024 | Iu, David S.; Maya, Jessica; Vu, Luyen T.; Fogarty, Elizabeth A.; McNairn, Adrian J.; Ahmed, Faraz; Franconi, Carl J.; Munn, Paul R.; Grenier, Jennifer K.; Hanson, Maureen R.; Grimson, Andrew

Associated cohorts

Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - IOM (Institute of Medicine) 2015 criteria, Post-exertional malaise (PEM)

Immunometabolic changes and potential biomarkers in CFS peripheral immune cells revealed by single-cell RNA sequencing

2024 | Sun, Yujing; Zhang, Zhenhua; Qiao, Qincheng; Zou, Ying; Wang, Lina; Wang, Tixiao; Lou, Bo; Li, Guosheng; Xu, Miao; Wang, Yanxiang; Zhang, Zhenhong; Hou, Xinguo; Chen, Li; Zhao, Ruxing

Associated cohorts

Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - Fukuda criteria, ME/CFS - IOM (Institute of Medicine) 2015 criteria, Post-exertional malaise (PEM)