TNF

tumor necrosis factor

Details

HGNC: HGNC:11892
GeneCards: TNF
NCBI: 7124
Ensembl: ENSG00000232810
UniProt: P01375
OMIM: 191160
UCSC: uc011fee.4
VEGA: OTTHUMG00000031194
ENA: X02910

Alias Symbols: TNFSF2, DIF, TNF-alpha
Previous Symbols: TNFA
Alias Names: "TNF superfamily, member 2"
Previous Names: "tumor necrosis factor (TNF superfamily, member 2)"

Associated Studies

Multifaceted evolution focused on maximal exploitation of domain knowledge for the consensus inference of Gene Regulatory Networks

2025 | Segura-Ortiz, Adrián; Giménez-Orenga, Karen; García-Nieto, José; Oltra, Elisa; Aldana-Montes, José F.

Associated cohorts
Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - ICC Criteria, Post-exertional malaise (PEM)
Phenotype: Fibromyalgia, Fibromyalgia - 1990 ACR (American College of Rheumatology) criteria, Fibromyalgia - 2011 ACR (American College of Rheumatology) criteria, ME/CFS, ME/CFS - CCC criteria, ME/CFS - ICC Criteria, Post-exertional malaise (PEM)
Phenotype: Fibromyalgia, Fibromyalgia - 1990 ACR (American College of Rheumatology) criteria, Fibromyalgia - 2011 ACR (American College of Rheumatology) criteria

Widespread Myalgia and Chronic Fatigue: Phagocytes from Macrophagic Myofasciitis Patients Exposed to Aluminum Oxyhydroxide-Adjuvanted Vaccine Exhibit Specific Inflammatory, Autophagic, and Mitochondrial Responses

2024 | Masson, Jean-Daniel; Badran, Ghidaa; Gherardi, Romain K.; Authier, François-Jérôme; Crépeaux, Guillemette

Associated cohorts
Phenotype: Chronic fatigue, Macrophagic myofasciitis, Myalgia

Transcriptional reprogramming primes CD8+ T cells toward exhaustion in Myalgic encephalomyelitis/chronic fatigue syndrome

2024 | Iu, David S.; Maya, Jessica; Vu, Luyen T.; Fogarty, Elizabeth A.; McNairn, Adrian J.; Ahmed, Faraz; Franconi, Carl J.; Munn, Paul R.; Grenier, Jennifer K.; Hanson, Maureen R.; Grimson, Andrew

Associated cohorts
Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - IOM (Institute of Medicine) 2015 criteria, Post-exertional malaise (PEM)

Metabolomic and immune alterations in long COVID patients with chronic fatigue syndrome

2024 | Saito, Suguru; Shahbaz, Shima; Luo, Xian; Osman, Mohammed; Redmond, Desiree; Cohen Tervaert, Jan Willem; Li, Liang; Elahi, Shokrollah

Associated cohorts
Phenotype: Long COVID, ME/CFS

Identification of CD8 T-cell dysfunction associated with symptoms in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and Long COVID and treatment with a nebulized antioxidant/anti-pathogen agent in a retrospective case series

2024 | Gil, Anna; Hoag, George E.; Salerno, John P.; Hornig, Mady; Klimas, Nancy; Selin, Liisa K.

Associated cohorts
Phenotype: ME/CFS, ME/CFS - IOM (Institute of Medicine) 2015 criteria, Post-exertional malaise (PEM)
Phenotype: Long COVID

Diverse immunological dysregulation, chronic inflammation, and impaired erythropoiesis in long COVID patients with chronic fatigue syndrome

2024 | Saito, Suguru; Shahbaz, Shima; Osman, Mohammed; Redmond, Desiree; Bozorgmehr, Najmeh; Rosychuk, Rhonda J.; Lam, Grace; Sligl, Wendy; Cohen Tervaert, Jan Willem; Elahi, Shokrollah

Associated cohorts
Phenotype: Long COVID
Phenotype: Long COVID, ME/CFS, Post-exertional malaise (PEM)

Association of circulating biomarkers with illness severity measures differentiates myalgic encephalomyelitis/chronic fatigue syndrome and post-COVID-19 condition: a prospective pilot cohort study

2024 | Domingo, Joan Carles; Battistini, Federica; Cordobilla, Begoña; Zaragozá, Maria Cleofé; Sanmartin-Sentañes, Ramón; Alegre-Martin, Jose; Cambras, Trinitat; Castro-Marrero, Jesus

Associated cohorts
Phenotype: ME/CFS, ME/CFS - ICC Criteria, Post-exertional malaise (PEM)
Phenotype: Long COVID, Long COVID - 2021 WHO criteria

The persistent viral infections in the development and severity of myalgic encephalomyelitis/chronic fatigue syndrome

2023 | Rasa-Dzelzkaleja, Santa; Krumina, Angelika; Capenko, Svetlana; Nora-Krukle, Zaiga; Gravelsina, Sabine; Vilmane, Anda; Ievina, Lauma; Shoenfeld, Yehuda; Murovska, Modra

Associated cohorts
Phenotype: ME/CFS, ME/CFS - Fukuda criteria

Proteomics and cytokine analyses distinguish myalgic encephalomyelitis/chronic fatigue syndrome cases from controls

2023 | Giloteaux, Ludovic; Li, Jiayin; Hornig, Mady; Lipkin, W. Ian; Ruppert, David; Hanson, Maureen R.

Associated cohorts
Phenotype: ME/CFS, ME/CFS - Fukuda criteria

Circulating miRNAs Expression in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

2023 | Soffritti, Irene; Gravelsina, Sabine; D’Accolti, Maria; Bini, Francesca; Mazziga, Eleonora; Vilmane, Anda; Rasa-Dzelzkaleja, Santa; Nora-Krukle, Zaiga; Krumina, Angelika; Murovska, Modra; Caselli, Elisabetta

Associated cohorts
Phenotype: ME/CFS, ME/CFS - Fukuda criteria