TNF

tumor necrosis factor

Details

HGNC
HGNC:11892
GeneCards
TNF
NCBI
7124
Ensembl
ENSG00000232810
UniProt
P01375
OMIM
191160
UCSC
uc011fee.4
VEGA
OTTHUMG00000031194
ENA
X02910
Alias Symbols
TNFSF2, DIF, TNF-alpha
Previous Symbols
TNFA
Alias Names
"TNF superfamily, member 2"
Previous Names
"tumor necrosis factor (TNF superfamily, member 2)"

Associated Studies

Multifaceted evolution focused on maximal exploitation of domain knowledge for the consensus inference of Gene Regulatory Networks

2025 | Segura-Ortiz, Adrián; Giménez-Orenga, Karen; García-Nieto, José; Oltra, Elisa; Aldana-Montes, José F.

Associated cohorts
Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - ICC Criteria, Post-exertional malaise (PEM)
Phenotype: Fibromyalgia, Fibromyalgia - 1990 ACR (American College of Rheumatology) criteria, Fibromyalgia - 2011 ACR (American College of Rheumatology) criteria, ME/CFS, ME/CFS - CCC criteria, ME/CFS - ICC Criteria, Post-exertional malaise (PEM)
Phenotype: Fibromyalgia, Fibromyalgia - 1990 ACR (American College of Rheumatology) criteria, Fibromyalgia - 2011 ACR (American College of Rheumatology) criteria

Widespread Myalgia and Chronic Fatigue: Phagocytes from Macrophagic Myofasciitis Patients Exposed to Aluminum Oxyhydroxide-Adjuvanted Vaccine Exhibit Specific Inflammatory, Autophagic, and Mitochondrial Responses

2024 | Masson, Jean-Daniel; Badran, Ghidaa; Gherardi, Romain K.; Authier, François-Jérôme; Crépeaux, Guillemette

Associated cohorts
Phenotype: Chronic fatigue, Macrophagic myofasciitis, Myalgia

Transcriptional reprogramming primes CD8+ T cells toward exhaustion in Myalgic encephalomyelitis/chronic fatigue syndrome

2024 | Iu, David S.; Maya, Jessica; Vu, Luyen T.; Fogarty, Elizabeth A.; McNairn, Adrian J.; Ahmed, Faraz; Franconi, Carl J.; Munn, Paul R.; Grenier, Jennifer K.; Hanson, Maureen R.; Grimson, Andrew

Associated cohorts
Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - IOM (Institute of Medicine) 2015 criteria, Post-exertional malaise (PEM)

Identification of CD8 T-cell dysfunction associated with symptoms in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and Long COVID and treatment with a nebulized antioxidant/anti-pathogen agent in a retrospective case series

2024 | Gil, Anna; Hoag, George E.; Salerno, John P.; Hornig, Mady; Klimas, Nancy; Selin, Liisa K.

Associated cohorts
Phenotype: ME/CFS, ME/CFS - IOM (Institute of Medicine) 2015 criteria, Post-exertional malaise (PEM)
Phenotype: Long COVID

Diverse immunological dysregulation, chronic inflammation, and impaired erythropoiesis in long COVID patients with chronic fatigue syndrome

2024 | Saito, Suguru; Shahbaz, Shima; Osman, Mohammed; Redmond, Desiree; Bozorgmehr, Najmeh; Rosychuk, Rhonda J.; Lam, Grace; Sligl, Wendy; Cohen Tervaert, Jan Willem; Elahi, Shokrollah

Associated cohorts
Phenotype: Long COVID
Phenotype: Long COVID, ME/CFS, Post-exertional malaise (PEM)

Association of circulating biomarkers with illness severity measures differentiates myalgic encephalomyelitis/chronic fatigue syndrome and post-COVID-19 condition: a prospective pilot cohort study

2024 | Domingo, Joan Carles; Battistini, Federica; Cordobilla, Begoña; Zaragozá, Maria Cleofé; Sanmartin-Sentañes, Ramón; Alegre-Martin, Jose; Cambras, Trinitat; Castro-Marrero, Jesus

Associated cohorts
Phenotype: ME/CFS, ME/CFS - ICC Criteria, Post-exertional malaise (PEM)
Phenotype: Long COVID, Long COVID - 2021 WHO criteria

Proteomics and cytokine analyses distinguish myalgic encephalomyelitis/chronic fatigue syndrome cases from controls

2023 | Giloteaux, Ludovic; Li, Jiayin; Hornig, Mady; Lipkin, W. Ian; Ruppert, David; Hanson, Maureen R.

Associated cohorts
Phenotype: ME/CFS, ME/CFS - Fukuda criteria