Dysregulation of tetrahydrobiopterin metabolism in myalgic encephalomyelitis/chronic fatigue syndrome by pentose phosphate pathway

Authors: Bulbule, Sarojini; Gottschalk, Carl Gunnar; Drosen, Molly E.; Peterson, Daniel; Arnold, Leggy A.; Roy, Avik

Journal of Central Nervous System Disease, 19 Aug 2024

View article | Discussion on S4ME

Cohorts in this study

Phenotype: ME/CFS, Orthostatic intolerance (OI)

DHFR, G6PD, GAPDH, GCH1, NOS3, PAH, PCBD1, PGLS, PTS, QDPR, TALDO1

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Notes

ME/CFS criteria detailed in previous paywalled article.

Data from:
- Section "Upregulation of BH4 Biosynthetic Genes in ME + OI Subjects"