EBV/HHV-6A dUTPases contribute to myalgic encephalomyelitis/chronic fatigue syndrome pathophysiology by enhancing TFH cell differentiation and extrafollicular activities

Authors: Cox, Brandon S.; Alharshawi, Khaled; Mena-Palomo, Irene; Lafuse, William P.; Ariza, Maria Eugenia

JCI Insight, 8 Jun 2022

View article | Discussion on S4ME


Cohorts in this study

Phenotype: ME/CFS, ME/CFS - CCC criteria, ME/CFS - Fukuda criteria, Post-exertional malaise (PEM)

BCL6, CXCR5, IL21, INHBA, PDCD1

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Phenotype: Gulf War syndrome

IL21, INHBA

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Notes

Data from:
- Section "ME/CFS sera exhibit heightened levels of activin A and IL-21"
- Fig 2B, 2C