A first study of cytokine genomic polymorphisms in CFS: Positive association of TNF-857 and IFNgamma 874 rare alleles

Authors: N. Carlo-Stella; C. Badulli; A. De Silvestri; L. Bazzichi; M. Martinetti; L. Lorusso, S; Bombardieri, L; Salvaneschi; M. Cuccia

Clinical and Experimental Rheumatology, 2006

PubMed | Discussion on S4ME


Cohorts in this study

Phenotype: ME/CFS, ME/CFS - Fukuda (1994 CDC)

IFNG, TNF

Search for these genes


Notes

Main finding: "There is a highly significant increase of TNF -857 TT and CT genotypes (p = 0.002) among patients with respect to controls and a significant decrease of IFN gamma low producers (A/A) (p = 0.04) among patients with respect to controls."