A network medicine approach to investigating ME/CFS pathogenesis in severely ill patients: a pilot study

Authors: Hung, Li-Yuan; Wu, Chan-Shuo; Chang, Chia-Jung; Li, Peng; Hicks, Kimberly; Dibble, Joshua J.; Morrison, Braxton; Smith, Chimere L.; Davis, Ronald W.; Xiao, Wenzhong

Frontiers in Human Neuroscience, 10 Feb 2025

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Phenotype: ME/CFS, ME/CFS - International Consensus Criteria (ICC), Post-exertional malaise (PEM)

ACADL, BRCA1, CFTR, COX10, HABP2, MFRP, PCLO, PRKN, ZFPM2

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Notes

9 genes found to contain pathogenic variants in at least 2 of the 20 patients.