Abnormalities of AMPK Activation and Glucose Uptake in Cultured Skeletal Muscle Cells from Individuals with Chronic Fatigue Syndrome

Authors: Brown, Audrey E.; Jones, David E.; Walker, Mark; Newton, Julia L.

PLOS ONE, 2 Apr 2015

View article | Discussion on S4ME

Cohorts in this study

Phenotype: ME/CFS, ME/CFS - Fukuda (1994 CDC)

IL6, MYOG, PRKAA2

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Notes

Based on: "In the basal state, CFS cultures showed increased myogenin expression but decreased IL6 secretion during differentiation compared with control cultures. Control cultures subjected to 16h EPS showed a significant increase in both AMPK phosphorylation and glucose uptake compared with unstimulated cells."