Combinations of Single Nucleotide Polymorphisms in Neuroendocrine Effector and Receptor Genes Predict Chronic Fatigue Syndrome

Authors: Goertzel, Benjamin N; Pennachin, Cassio; de Souza Coelho, Lucio; Gurbaxani, Brian; Maloney, Elizabeth M; Jones, James F

Pharmacogenomics, Apr 2006

View article | PubMed | Discussion on S4ME

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Phenotype: ME/CFS, ME/CFS - Reeves 2005 Criteria

COMT, NR3C1, TPH2

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Notes

"The top three genes containing the SNPs accounting for the highest accumulated importances were neuronal tryptophan hydroxylase (TPH2), catechol-O-methyltransferase (COMT) and nuclear receptor subfamily 3, group C, member 1 glucocorticoid receptor (NR3C1)."