Microvascular Remodeling and Endothelial Dysfunction Across Post-COVID-19 and ME/CFS: Insights from the All Eyes on PCS Study

Authors: Wallraven, Timon; Günthner, Roman; Lethen, Isabelle; Ribeiro, Andrea; Lech, Maciej; Oertel, Frederike Cosima; Reeß, Lukas G.; Haller, Bernhard; Streese, Lukas; Hanssen, Henner; Wunderle, Michael; Schmaderer, Christoph

25 Jan 2026 (Preprint)

View article | Discussion on S4ME

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Phenotype: Long COVID, ME/CFS, ME/CFS - Canadian Consensus Criteria (CCC) 2003, Post-exertional malaise (PEM)

ICAM1, IL6, VCAM1

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Notes

"We additionally compared laboratory variables and circulating biomarkers between non-ME/CFS (recovered and PCS) with ME/CFS patients after correction for age. As shown in PCS patients, markers of ED (VCAM-1, ICAM-1) and inflammation (IL-6) were associated with ME/CFS status (Figure 5 h)."