Multi-omics identifies lipid accumulation in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome cell lines: a case-control study

Authors: Missailidis, Daniel; Armstrong, Christopher W.; Anderson, Dovile; Allan, Claire Y.; Sanislav, Oana; Smith, Paige K.; Esmaili, Tammy; Creek, Darren J.; Annesley, Sarah J.; Fisher, Paul R.

Journal of Translational Medicine, 8 Jan 2026

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Phenotype: ME/CFS, ME/CFS - Canadian Consensus Criteria (CCC) 2003, Post-exertional malaise (PEM)

CDS2, CEPT1, DGKE, MBOAT1, PEMT, PISD, PLD2, PTDSS1

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Notes

"BioPAN pathway analysis of our lipidomic dataset was undertaken [...] Of the 43 gene products identified by BioPAN, 25 were detected in our gene expression datasets and 8 of these were differentially expressed"