WASF3 disrupts mitochondrial respiration and may mediate exercise intolerance in myalgic encephalomyelitis/chronic fatigue syndrome

Authors: Wang, Ping-yuan; Ma, Jin; Kim, Young-Chae; Son, Annie Y.; Syed, Abu Mohammad; Liu, Chengyu; Mori, Mateus P.; Huffstutler, Rebecca D.; Stolinski, JoEllyn L.; Talagala, S. Lalith; Kang, Ju-Gyeong; Walitt, Brian T.; Nath, Avindra; Hwang, Paul M.

Proceedings of the National Academy of Sciences, 14 Aug 2023

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Notes

• "significantly increased WASF3 levels"
• "Indeed, the ER stress marker PERK was significantly higher while BiP was lower in the ME/CFS muscle samples."
• MTCO1 and COX17 from fig. 5B